Crizalk 200mg Capsule - Crizotinib Uses & Side effects

CRIZALK 200MG


DESCRIPTION


Crizalk 200mg capsule is used for the therapy of patients with metastatic non-small cell lung cancer.

Crizalk 200mg belongs to type of tyrosine kinase inhibitor. Kinases are enzymes which are included in many functions, involving cell development and reproduction.


MECHANISM OF ACTION


More specifically, crizotinib inhibits anaplastic lymphoma kinase (ALK), hepatocyte growth factor receptor (HGFR, c-MET), and Recepteurd'OrigineNantais (RON). 
Deformity in the ALK gene result by mutations or translocations may causes expression of oncogenic fusion proteins. Certain patients with NSCLC, they have the EML4-ALK gene.


PRODUCT DETAILS


Brand            Crizalk
Ingredients    Crizotinib
Strength            200mg
Manufactured    Pfizer Ltd


CRIZOTINIB SIDE EFFECTS


Infection increased
Breathlessness
Eyesight changes
Bowel changes
Feeling sick
Swelling of hands and feet’s
Decreased appetite
Fatigue
Liver changes
Skin rash
bradycardia


PREGNANCY


Based on studies of animal and mechanism of action, Crizalk 200mg will cause fetal harm when given to pregnant women. Advice the female not to become pregnant while on treatment with Crizalk 200mg



PRESCRIPTION

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