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Crizalk 250mg Capsule- Crizotinib Uses & Side effects

CRIZALK 250MG DESCRIPTION Crizalk 250mg capsule is used for the therapy of patients with metastatic non-small cell lung cancer. Crizalk 250mg inhibits the anaplastic lymphoma kinase (ALK) and the c-MET/hepatocyte growth factor receptor. This action disturbs certain pathways in the cell, which can inhibit the growth of tumor cells. It is made specifically for the treatment of a type of lung cancer in which ALK is overactive due to an abnormality in the ALK gene. EXCRETION Crizalk is excreted via feces 63% and 22% via urine and half -life is 42 hours PRODUCT DETAILS Brand            Crizalk Ingredients     Crizotinib Strength            250mg Manufactured    Pfizer Ltd CRIZOTINIB SIDE EFFECTS • Infection increased • Breathlessness • Eyesight changes • Bowel changes • Feeling sick • Swelling of hands and feet’s • Decreased appetite...

Crizalk 200mg Capsule - Crizotinib Uses & Side effects

CRIZALK 200MG DESCRIPTION Crizalk 200mg capsule is used for the therapy of patients with metastatic non-small cell lung cancer. Crizalk 200mg belongs to type of tyrosine kinase inhibitor. Kinases are enzymes which are included in many functions, involving cell development and reproduction. MECHANISM OF ACTION More specifically, crizotinib inhibits anaplastic lymphoma kinase (ALK), hepatocyte growth factor receptor (HGFR, c-MET), and Recepteurd'OrigineNantais (RON).  Deformity in the ALK gene result by mutations or translocations may causes expression of oncogenic fusion proteins. Certain patients with NSCLC, they have the EML4-ALK gene. PRODUCT DETAILS Brand            Crizalk Ingredients    Crizotinib Strength            200mg Manufactured    Pfizer Ltd CRIZOTINIB SIDE EFFECTS • Infection increased • Breathlessness • Eyesight changes • Bowel ...