Lanib 250mg (Lapatinib) tablets - Uses & Side effects

Lanib 250mg


Lanib consist of Lapatinib is primarily indicated for advanced breast cancer.

Lanib is used in combination with capecitabine with Lanib tablets are usually indicated for the treatment of metastatic breast cancer patients in whose cancer cells expressed with EGFR 2 (HER2) and patients may already receive an anthracycline, taxane& Transtuzumab.

PRODUCT DETAILS:

Brand Lanib
Ingredients Lapatinib
Strength 250mg
Manufactured BDR



Lanib



OVER DOSAGE:

The doses of Lanib ranges from 2500mg to 9000mg daily, the duration of therapy should be varied between 1 & 17 days. Symptoms occurred during over dose of Lanib are Sore scalp, sinus tachycardia & mucosal inflammation. Patients should be providing with supportive measures. Hemodialysis is not an effective method for overcoming the over dosage condition of Lanib.


SIDE EFFECTS:

Diarrhea, Nausea, Vomiting, Stomatitis, Back pain, Dyspnea, Insomnia, Elevation of hemoglobulin, platelets, neutrophils, Increase in AST & ALT, bilirubin, Alopecia, Pruritus, Nail disorders, Asthenia, Headache, Epistaxis, Reduction of left ventricular ejection fraction, Liver toxicity, Interstitial lung disease, Anaphylactic reactions, Stevens Johnson syndrome, Ventricular arrhythmias, QT prolongation.


DRUG- DRUG INTERACTION:


Lanib 250mg tablets are inhibition of CYP3A4, CYP2C8 & P-gp drug transporters; weak inhibitor of CYP3A4. The dose reduction of these concurrent uses of substrate drug should be advised, while allowing Lanib combined with drugs metabolized by CYP3A4, CYP2C8 or P-gp.



PRESCRIPTION

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