Lapahope 250mg Tablet: Lapatinib Usage & Side effects | Blueberrypharma

Lapahope 250MG




Lapahope 250mg tablets are categorized as anti-neoplastic agent, which is orally active drug used for treating breast cancer.
Lapahope tablets are comes under biological category which is targeted chemotherapy.
Lapahope tablets are classified as;
1. Tyrosine kinase prohibitor
2. Stop the HER2/neu& epidermal growth factor receptor activity
3. Targeted therapy 
4. Signal transduction prohibitor


MECHANISM OF ACTION

Chemically Lapatinib is categorized as 4-anilinoquinazoline derivative, which expels anti-cancer activity by prohibiting intracellular tyrosine kinase domains of EFGR & HER type 2. The ErbB driven tumor cell production has been prohibited by Lapatinib. This growth factor receptor present on cell surface of tumors which may leads to cause cell death.


PRODUCT DETAILS

Brand                  Lapahope
Ingredients          Lapatinib
Strength              250mg
Manufactured      Natco


METABOLISM

Lapatinib is a substrate of P-gp& BCRP and undergoes intensive metabolism by using CYPP3A4 & CYP3A5 with lesser contribution of CYP2C19 & CYP2C8.


SIDE EFFECTS

Diarrhea, Nausea, Vomiting, Stomatitis, Back pain, Dyspnea, Insomnia, Elevation of hemoglobulin, platelets, neutrophils, Increase in AST & ALT, bilirubin, Alopecia, Pruritus, Nail disorders, Asthenia, Headache, Epistaxis, Reduction of left ventricular ejection fraction, Liver toxicity, Interstitial lung disease, Anaphylactic reactions, Stevens Johnson syndrome, Ventricular arrhythmias, QT prolongation


MISSED DOSE

Missed dose should be skipped and follow the regular dosing schedule for avoiding adverse conditions. If missed dose occurs, it should not be resume and continue the next schedule.



PRESCRIPTION

Blueberrypharma.com, a fully licensed and regulated pharmacy medicine, takes all precautions to strictly abide by the laws and regulations set forth in the dispensing of prescription medications. By placing the order for your prescription medicines, you acknowledge and accept the following terms regarding the purchase of any prescription medicines.

Comments

Post a Comment

Popular posts from this blog

Xtandi 40mg tablet - Uses & Side effects

Image
Xtandi 40mg Xtandi capsules belongs to nonsteroidal antiandrogen drug which is indicated for use in conjunction with castration to treat metastatic castration-resistant prostate cancer (mCRPC).  Xtandi 40mg capsule  is in the form of liquid – filled soft gelatin capsules administer via oral route. Each capsule consists of 40mg enzalutamide in the form of solution in caprylocaproyl polyoxylglycerides. PRODUCT DETAILS Brand Xtandi Ingredients Enzalutamide Strength 40mg Manufactured Astellas Xtandi 40mg tablet OVER DOSAGE In overdose condition treatment with Xtandi 40mg solid be stop and provide supportive measures care and monitor the vital signs. Multiple dose If administer ≤ 240mg no seizures is reported but when taking 360mg,480mg, and 600mg daily then 3 seizures were absorbed. If overdose occur, the patient will have high risk of seizures. ENZALUTAMIDE SIDE EFFECTS MORE COMMON Back pain; bloating of the face, arms, hands, ...
Read more

Crizalk 250mg Capsule- Crizotinib Uses & Side effects

CRIZALK 250MG DESCRIPTION Crizalk 250mg capsule is used for the therapy of patients with metastatic non-small cell lung cancer. Crizalk 250mg inhibits the anaplastic lymphoma kinase (ALK) and the c-MET/hepatocyte growth factor receptor. This action disturbs certain pathways in the cell, which can inhibit the growth of tumor cells. It is made specifically for the treatment of a type of lung cancer in which ALK is overactive due to an abnormality in the ALK gene. EXCRETION Crizalk is excreted via feces 63% and 22% via urine and half -life is 42 hours PRODUCT DETAILS Brand            Crizalk Ingredients     Crizotinib Strength            250mg Manufactured    Pfizer Ltd CRIZOTINIB SIDE EFFECTS • Infection increased • Breathlessness • Eyesight changes • Bowel changes • Feeling sick • Swelling of hands and feet’s • Decreased appetite...
Read more

Crizalk 200mg Capsule - Crizotinib Uses & Side effects

CRIZALK 200MG DESCRIPTION Crizalk 200mg capsule is used for the therapy of patients with metastatic non-small cell lung cancer. Crizalk 200mg belongs to type of tyrosine kinase inhibitor. Kinases are enzymes which are included in many functions, involving cell development and reproduction. MECHANISM OF ACTION More specifically, crizotinib inhibits anaplastic lymphoma kinase (ALK), hepatocyte growth factor receptor (HGFR, c-MET), and Recepteurd'OrigineNantais (RON).  Deformity in the ALK gene result by mutations or translocations may causes expression of oncogenic fusion proteins. Certain patients with NSCLC, they have the EML4-ALK gene. PRODUCT DETAILS Brand            Crizalk Ingredients    Crizotinib Strength            200mg Manufactured    Pfizer Ltd CRIZOTINIB SIDE EFFECTS • Infection increased • Breathlessness • Eyesight changes • Bowel ...
Read more